徐晓飞
基本信息
学位:工学博士
学术/专业学位硕士研究生导师
E-mail： xfxufe@taihepaimai.com
通讯地址广东省阳江市江城区罗琴路1号�？坡�402A
个人简介
1979年生，博士后、高级工程师，现任广东海洋大学食品科学与工程学院教师，曾任无限极(中国)有限公司研发高级主任、仙乐健康科技股份有限公司研发高级经理、华南协同创新研究院生物活性分子开发与应用创新中心副主任。先后主持博士后科学基金（面上项目和特别资助）、中央高校基本科研业务经费项目、省科技专项和企业横向课题等十余项。主讲课程为食品化学、保健食品原理与功能评价、创新创业和食品工厂设计。在企业逾20年营养补充剂及保健食品/功能食品研发经验，擅长天然活性成分挖掘与产业化开发，已开发上市营养保健/功能食品逾六十余款，年销售额过百亿元，代表性产品有无限极增健口服液、无限极源适餐粉/源乐餐粉、无限极元泰片、千林柠檬酸钙片以及维乐维营养软糖系列、燃小乙体重管理产品、UKDNA银耳胶原蛋白肽、绣球菌浓缩冻干片等，申请专利20余项（授权中国专利18项，美国专利1项），主导开发获批功能性中草药保健食品批文10项，参编并主持开发两项功能食品因子多糖检测方法入编《保健食品功效成分检测方法》书籍，发表国内外学术期刊论文70余篇。
研究方向
1.食用菌来源（香菇、茯苓、银耳、绣球菌等）天然多糖的结构、功能和机理研究
2.药食同源资源的产业化开发、深加工技术研究
3.特色鲜明的保健食品、功能食品、营养补充剂等食品开发、产品功效及机理研究
4.多糖原料、功能/保健食品中多糖检测方法研究
主持/参与科研项目
1.广东省科学技术厅，2022省科技专项资金（“大专项+任务清单”）项目—阳江山药深加工产业化技术研究与产品开发
2.广东省科学技术厅，广东省重点领域研发计划—食品控糖降脂活性成分结构解析、定向富集和产业化应用 2021B0707060001
3.科技部，2018年国家重点研发计划“食品安全关键技术研发”重点专项子课题2018YFC1602102，保健食品生产加工过程风险评价技术
4.中国博士后科学基金会，第九批博士后科学基金特别资助，2016T90787
5.华南理工大学中央高�？蒲芯炎匀豢蒲钅浚�2015ZM164
6.中国博士后科学基金会，第57批面上资助，2015M572324
7.企业横向项目：功能食品和日化产品开发；
8.企业横向项目：绣球菌功能食品开发与产业化；
9.企业横向项目：食用菌多糖工艺开发
主要论文
1. Xu Xiaofei*, Liu Xiaofei, Liu Liyan, Chen Jin, Guan Jingjing, Luo Donghui. Metagenomic and transcriptomic profiling of the hypoglycemic and hypotriglyceridemic actions ofTremella fuciformis-derived polysaccharides in high-fat-diet- and streptozotocin-treated mice. Food&Function. 2024, 15(22):11096-11114.
2. Xu Yuanyuan, Xiaofei Liu, Jingjing Guan, Jin Chen,Xiaofei Xu*. iTRAQ-Based Proteomic Profiling of Skin Aging Protective Effects ofTremella fuciformis-Derived Polysaccharides on D-Galactose-Induced Aging Mice, Molecules,2024. 29, no. 21: 5191.
3.徐晓飞,陈萌,谢英洁,吴丰魏.基于iTRAQ蛋白质组学技术分析羧甲基茯苓多糖对老龄小鼠免疫功能和血脂调节的机理.食品科学技术学报，2024，42(6):54 -67.
4.叶鹏,徐晓飞*,何瑞琪.绣球菌功能食品对敏感性皮肤人群的作用研究.食用菌,2024,46（2）：66-72.
6. Luo Donghui, Liu Xiaofei, Guan Jinjin, Chen Jin,Xu Xiaofei*. Effects ofTremella fuciformis-derived polysaccharides with different molecular weight on D-galactose-induced aging of mice. Polish Journal of Food and Nutrition Sciences. 2023;73(2):163-174.
7. Luo Donghui, Zhang Xuewu,Xu Xiaofei*.1H NMR-based urinary metabolic analysis of high-dose cyclophosphamide-induced toxicity in mice. Analytical Biochemistry. 2023, 670:115138.
8.徐媛媛,陈萌,徐晓飞*,何瑞琪.绣球菌浓缩液抑制黑色素合成和抗氧化活性研究.食品安全质量检测学报, 2023, 14(17):261-268.
9.徐晓飞，何瑞琪，宗敏华，罗东辉，邱树毅.红曲霉代谢产物的调控及在酿酒中的应用研究进展.中国酿造, 2023, 42(4): 8-13.
10.徐晓飞,罗东辉,赵明月,钟兴伟.两种银耳多糖对小鼠抗衰作用的比较.食用菌学报. 2022, 38 (02): 93-102.
11.徐晓飞,赵明月,钟兴伟等.胶原蛋白肽复合银耳多糖对D-半乳糖致衰小鼠的改善作用.中国食品学报, 2022, 22(10):134-142.
12. Liu Xiaofei, Luo Donghui, Guan Jinjin, Chen Jin,Xu Xiaofei*. Mushroom polysaccharides with potential in anti-diabetes: Biological mechanisms, extraction, and future perspectives: A review. Frontiers in Nutrition. 2022; 9:1087826.
13. Luo Donghui, Guan Jingjing, Dong Hao*, Chen Jin, Liang Ming, Zhou Chunxia, Xian Yanpin,Xu Xiaofei*. Simultaneous determination of twelve mycotoxins in edible oil, soy sauce and bean sauce by PRiME HLB solid phase extraction combined with HPLC-Orbitrap HRMS. Frontiers in Nutrition. 2022; 9:1001671.
14.徐晓飞，钟兴伟，赵明月，何瑞琪.胶原蛋白肽与银耳多糖对衰老小鼠皮肤改善作用及机理研究.食品工业科技，2022，43（8）：357?364.
15.刘星汶,杨继国,徐晓飞*.羧甲基茯苓多糖的水媒法制备及其免疫活性研究.菌物学报, 2021, 40(6): 1575-1582.
16.何瑞琪,赵明月,钟兴伟,徐晓飞*.含胶原蛋白肽饮品对衰老小鼠皮肤改善作用和抗氧化作用研究.食品安全质量检测学报, 2021, 12(19):8.
17. Liu Xiaofei, Wang Xiaoqin,Xu Xiaofei, Zhang Xuewu. Purification, antitumor and anti-inflammation activities of an alkali-soluble and carboxymethyl polysaccharide CMP33 fromPoria cocos. International Journal of Biological Macromolecules, 2019, 127: 39-47.
18.徐晓飞,陈慧萍,杨继国.儿童消化系统发育生理研究进展.中国儿童保健杂志, 2019, 27(11):1196-1200.
19. Liu Xiaofei, Yu Xiuting,Xu Xiaofei, Zhang Xuewu. The protective effects ofPoria cocos-derived polysaccharide CMP33 against IBD in mice and its molecular mechanism. Food & Function, 2018, 9(11): 5936-5949.
20.徐晓飞,钟浩权,刘玮,夏晚霞,杨继国.体外模拟消化维生素C和钙软糖的动力学研究.现代食品科技, 2018, 34(11):89-94+280.
21.徐晓飞,钟浩权,夏晚霞,刘玮,杨继国.体外模拟消化多维锌软糖的研究.中国食品添加剂, 2018, 11:162-168.
22. Xu Xiaofei, Yang Jiguo, Ning Zhengxiang, Zhang Xuewu.1H NMR-based metabolic profiling of urine from mice fedLentinula edodes-derived polysaccharides. Polish Journal of Food and Nutrition Sciences. 2018;68(3):207–216.
23. Xu Xiaofei, Yang Jiguo, Ning Zhengxian, Zhang Xuewu.1H NMR-based metabolic investigation of the effect ofLentinula edodes-derived polysaccharides on aged mice. Journal of Food Biochemistry. 2017. 41:e12371.
24. Xu Xiaofei, Yang Jiguo, Ning Zhengxian, Zhang Xuewu. Proteomic analysis of intestinal tissues from mice fed1withLentinula edodes-derived polysaccharides. Food & Function. 2016. 7(1)：250-261.
25. Xu Xiaofei, Wang Zhujun, Zhang Xuewu. The human microbiota associated with overall health. Critical Reviews in Biotechnology. 2015, 35(1):129-140
26. Xu Xiaofei, Zhang Xuewu.Lentinula edodes-derived polysaccharide alters the spatial structure of gut microbiota in mice. PLoS One, 2015,10(1): e0115037
27. Xu Xiaofei, Yang Jiguo, Luo Zhen, Zhang Xuewu.Lentinula edodes-derived polysaccharide enhances systemic and mucosal immunity by spatial modulation of intestinal gene expression in mice. Food & Function, 2015, 6:2068-2080.
28. Xu Xiaofei, Yang Jiguo, Ning Zhengxian, Zhang Xuewu.Lentinula edodes-derived polysaccharide rejuvenates mice in terms of immune responses and gut microbiota. Food & Function, 2015, 6(8):2653-63.
29. Xu Xiaofei, Zhang Xuewu. Effects of cyclophosphamide on immune system and gut microbiota in mice. Microbiological Research. 2015, 171:97–106.
30. Xu Xiaofei, Yan Huidang, Tang Jian, Chen Jian, Zhang Xuewu. Polysaccharides inLentinus edodes: Isolation, structure, immuno-modulating activity and future prospective. Critical Reviews in Food Science and Nutrition. 2014; 54(4):474-87.
31. Xu Xiaofei, He Shengjie, Zhang Xuewu. New food safety concerns associated with gut microbiota. Trends in Food Science and Technology. 2013, 34(1): 62-66.
32. Xu Xiaofei, Xu Pingping, Zhang Xuewu. Gut Microbiota, Host Health and Polysaccharides. Biotechnology Advances. 2013. 31,318-37.
33. Xu Xiaofei, Yan Huidang, Zhang Xuewu. Structure and immuno-stimulating activities of a new heteropolysaccharide fromLentinula edodes. Journal Agricultural and Food Chemistry 2012.60, 11560-11566.
34. Xu Xiaofei, Yan Huidang, Chen Jian, Zhang. Xuewu. Bioactive proteins from mushrooms. Biotechnology Advances. 2011. 29,667-674
35.徐晓飞，张丙青，罗珍，陈健.不同产地香菇营养成分的比较研究，食用菌，2012，32:57.
36.徐晓飞，向莹，张小爽，陈健.不同干燥方式对香菇品质的影响[J].食品工业科技，2012，17:259.
37.徐晓飞，闫慧丹，罗珍，张学武.香菇多糖Lentinan的提取分离、生物活性和构效关系的研究进展.食品工业科技. 2012, 33:435.
38.徐晓飞，罗珍.多糖类保健品质量控制技术的研究进展.中国食物与营养. 2011. 9:18-20;
39.陈健,张灵芝,韦丁,徐晓飞.黑虎掌菌多糖的组成和抗肿瘤活性[J].华南理工大学学报(自然科学版), 2011, 39(12):110-114.
获奖
1.红曲酱香白酒，中国食品工业协会科学技术一等奖，2022
2.氧沁多糖刺梨生物发酵饮品，中国食品工业协会科学技术一等奖，2020
3.中草药活性多糖快速筛选、制备关键技术及产业化应用，江门市科学技术奖特等奖，2014.
